From Shaan Khan, CNN


October 11, 2012 -- Updated 1640 GMT (0040 HKT)









Pakistani politician Imran Khan addresses a peace rally against drone strikes in Tank, Pakistan ,on October 7. 2012 .






STORY HIGHLIGHTS



The attack targeted a militant's compound, officials say[/*]

The officials say the militant is affiliated with the Haqqani network[/*]

The U.S. carries out drone strikes in Pakistan but generally does not comment[/*][/list]

Islamabad, Pakistan (CNN) -- A suspected U.S. drone strike killed 16 people and wounded six Thursday in one of Pakistan's semi-autonomous tribal regions, two officials said.



The attack, which included four missiles, targeted a compound on the border of Orakzai Agency and North Waziristan, a local government official and a military official said.



The compound belonged to Maulvi Shakirullah, a militant affiliated with the Haqqani network, the officials said.



The network is widely viewed to be fueling the insurgency in Afghanistan



Pakistan's Geo TV, a CNN affiliate, also reported that the drone "fired four missiles at a madrasa," or seminary, run by Shakirullah.



A previous drone strike in the Orakzai agency in 2009 killed 11 suspected militants from a faction of the Pakistani Taliban.



The United States carries out drone strikes in Pakistan aimed at dismantling terror operations, but generally does not comment on them.



U.S. activists in Pakistan to protest drone strikes



5 killed in first drone strike since protest march



Read more: Why U.S. will live to regret drone strikes